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Fen River, Chinese (Pinyin) Fen He, or (Wade-Giles romanization) Fen Ho, river in Shanxi province, northern China. The Fen River is an eastern tributary of the Huang He (Yellow River).

After rising in the Guancen Mountains in northwestern Shanxi, it flows southeast into the basin of Taiyuan and then southwest through the central valley of Shanxi to join the Huang He near Hejin. Its total length is approximately 435 miles (700 km).

The Fen River and its tributaries drain the whole of central Shanxi. Its basin falls into several separate sections: the high and rugged plateau drained by its headwaters to the east of the Lüliang and Luya mountains; the extensive and heavily cultivated basin of Taiyuan; the narrow central valley, opening up into minor basins around Linfen and Quwu; and finally the plains area in which the Fen River turns sharply west to join the Huang He.

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The Fen River has a torrential course with steep gradients and rapids and has never been a useful waterway except in its lower reaches. Junk traffic is possible as far as Quwu (near Houma), and small craft can navigate as far as Linfen.

The plain around Taiyuan has extensive irrigation systems, of which the most important is the Guanghui Canal. The Fen River valley was an early centre of civilization and has remained an important route, linking the Beijing area with the strategically vital Shanxi province and with the major land routes to Central Asia via Gansu province.   Sarcoptic mange caused by the mite Sarcoptes scabiei is a worldwide disease affecting both humans and animals.  

Here we report the molecular characterization and evaluation of a recombinant S.

scabiei tropomyosin (Ss Tm) protein in a vaccination trial in rabbits. The full-length c DNA was cloned in a bacterial p ET vector, and the recombinant protein was expressed in BL21 (DE3) cells and purified.

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Using specific rabbit antiserum, tropomyosin was localized immunohistochemically in mite tissue sections. Vaccination trials with the recombiant Ss Tm was carried out in New Zealand rabbits. The full-length open reading frame (ORF) of the 852 bp cloned gene from S. The amino acid sequence showed 98.94%, 97.89% and 98.59% homology to Dermatophagoides farina and Dermatophagoides pteronyssinus group 10 allergens and Psoroptes ovis tropomyosin, respectively.

Tropomyosin was localized immunohistochemically in mite tissue sections mainly in the mouthparts, legs and integument of the epidermis.